Furthermore, the proposed sequence had signal curves that are smoother and less noisy. Changes in the myocardial location and geometry decreased by 50% in the slice tracking sequence. The proposed sequence was significantly better compared with the conventional perfusion sequence in terms of qualitative image scores. The location and geometry of the myocardium were quantitatively analyzed, and the perfusion signal curves were calculated from both sequences to show the efficacy of the proposed sequence. Images were compared with the conventional perfusion (i.e., without slice tracking) results from the same subjects. The proposed sequence was used to acquire CMR perfusion datasets in 12 healthy adult subjects and 8 patients. We propose to use a leading navigator, placed immediately before each 2D slice acquisition, for tracking the respiratory motion and updating the slice location in real-time. To develop a free-breathing cardiac MR perfusion sequence with slice tracking for use after physical exercise.
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